Blog

  • Current Challenges in #Bioinformatics According to #ScienceTwitter
    The results were pretty interesting and IMHO captures some salient points that would be important to know for anyone who develops bioinformatics software – commercial or otherwise.
  • How much Public #Microbiome or #Metagenomics data is out there?
    And … where is it located? I’ve been thinking about this topic a lot lately. One might quickly think that the answers are “a ton” and then “SRA?” and they would partly right. The real answer is “a shit ton” and “all over the place”. I mean literally millions of FASTQ files… located in databases far and wide way beyond just SRA. I’m attempting to catalog this data and capture a number of relevant additional data-points such as # projects, # samples, # libraries, types of libraries, etc. And for now – I’m mainly interested in data in the public…
  • The Commercial #Microbiome Market
    Now that #SFAF2019 is over and I have a few days to relax in sunny Santa Fe NM, I took some time to do a little reading and writing on some topics I’ve had on my mind lately. Recently at #SFAF2019, I had a chat with a colleague about the size and scope of the microbiome market. I was surprised they didn’t realize how rapidly this space was growing, and how many companies are operating in this space with specific solutions and products for both B2B and B2C markets. I’ve done a ton of analysis on this topic (far more…
  • Careers & The 3 Year Plan
    Recently on Twitter a thread by L. Maren Wood asked hiring managers to provide some tips for newly minted PhDs applying for “non-academic” jobs. I responded a couple times throughput the thread, but one thing I wanted to expand on was the notion of having A Plan and knowing ahead of time What you Are Working For. Although this was not directly related to applying for a job per se, it was still IMHO important and often overlooked aspect of being successful in interviewing and finding the job you want. All the other comments (not just mine) are also worth…
  • A Few Classics on #Genomics and the Origin of “Shotgun DNA Sequencing”
    I was on Spring Break recently, and I’m not entirely sure how I ended up doing this, but on the last day of my vacation I spent several hours chasing down and reading classical papers in #genomics and #bioinformatics. In some cases, these were papers I remembered from when I was back in grad’ school, but for others they were new to me – and thoroughly enjoyable to read. One of the main questions I was asking myself was “Who coined the phrase ‘shotgun sequencing’?” I then started digging. I was fairly certain this had to of been someone involved…

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